Improve the diagnostic potential of HNL even further

In our recent publication on fMLP-activated whole blood we showed that it was possible to achieve an even greater diagnostic distinction between acute infections caused by bacteria or virus by adding some other biomarkers to the algorithm. The distinction approached an unlikely 100% sensitivity and specificity by adding either serum concentrations of IP-10 and/or TRAIL to the diagnostic algorithm. In the same report the algorithm that had replaced HNL by CRP was good but obviously inferior to the inclusion of HNL Take a look at the figure at the bottom showing this by comparing areas under the ROC curve.