EPO (eosinophil peroxidase)

EPO is a very basic protein stored in and secreted from human eosinophil granulocytes. The main activity of EPO is that of a peroxidase, but other non-peroxidase activities have been identified. EPO is unique to eosinophils. EPO may be measured in various biological fluids as a reflection of the turnover and activity of the eosinophil population in the body. We provide you with the tools to study the involvement of EPO in human disease processes.

The mouse monoclonal antibody against EPO mab 673 of the IgG1-type is suitable for the identification of EPO in tissues by immunocytochemistry (available).

Native EPO purified from eosinophils of a patient with hypereosinophilia.

An ELISA assay for the measurement of EPO in various body fluids.